Stephen J. O'Brien, Ph.D.
Principal Investigator, Office of the Chief
[Biography] [Research] [Recent Publications]
{E-Mail Address} obrien@ncifcrf.gov
Recent Publications:
 | Lautenberger, J.A., Stephens, J.C., O’Brien, S.J. and Smith, M.W.: Significant admixture linkage disequilibrium across 30 cM around the FY locus in African Americans. Am. K. Hum. Genet. 66:969-978, 2000. |
| Johnson, W.E., F.
Shinyashiku, M. Menotti Raymond, C. Driscoll, C. Leh, M. Sunquist, L.
Johnston, M. Bush, D. Wildt, N. Yuhki, and S.J. O'Brien. 1999. Molecular
genetic characterization of two insular Asian cat species, Bornean Bay Cat
and Iriomote cat. Pp. 223-248 In: Evolutionary theory and processes: modern
perspectives (S.P. Wasser ed.). Klewar Academic Publishers.
| Johnson, W.E., J.
Pecon Slattery, E. Eizirik, J. Kim, M. Menotti Raymond, C. Bonacic, R.
Cambre, P. Crawshaw, A. Nunes, H. Seuanez, M. A. Moreira, K. L. Seymour, F.
Simon, W. Swanson, and S.J. O'Brien. 1999. Disparate phylogeographic
patterns of mitochondrial DNA variation in four closely related South
American small cat species. Molecular Ecology. 8:S79-S94.
| |
| Winkler C; Modi
W; Smith MW; Nelson GW; Wu X; Carrington M; Dean M; Honjo T; Tashiro K; Yabe
D; Buchbinder S; Vittinghoff E; Goedert JJ; O'Brien TR; Jacobson LP; Detels
R; Donfield S; Willoughby A; Gomperts E; Vlahov D; Phair J; O'Brien SJ.
Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant.
ALIVE Study, Hemophilia Growth and Development Study (HGDS),
Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort
Study (MHCS), San Francisco City Cohort.
Science 279:389-393,
1998
| Eizirik, E., S.L.
Bonatto, W.E. Johnson, P. Crawshaw, C. View, D. Brousset, S.J. O’Brien ,
and F.M. Salzano. 1998/ Phylogeographic patterns and population
structure of two neotropical cat species inferred from mitochondrial DNA
control region sequences. Journal of Molecular Evolution. 47:613-624.
| |
| Smith MW; Dean M; Carrington M; Winkler C; Huttley GA; Lomb DA; Goedert JJ; O'Brien TR; Jacobson LP; Kaslow R; Buchbinder S; Vittinghoff E; Vlahov D; Hoots K; Hilgartner MW; O'Brien SJ. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression. Hemophilia Growth and Development Study (HGDS), Multicenter AIDS Cohort Study (MACS), Multicenter Hemophilia Cohort Study (MHCS), San Francisco City Cohort (SFCC), ALIVE Study. Science 277:959-65, 1997 | ||||
| O'Brien SJ and
Dean M. In search of AIDS-resistance
genes. Sci. Amer. 277:
44-51, 1997
| O'Brien SJ.
The family line: The human-cat connection. National Geographic
Magazine 191:77-85, 1997
| O'Brien SJ;
Wienberg J; Lyons LA. Comparative
genomics: Lessons from cats. Trends
Genet 13: 393-399, 1997
| |
| O'Brien SJ. Genomic prospecting. Nature Med 1:742-744, 1995 |