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Cat/Human Parallel Radiation Hybrid Maps

Radiation hybrid map of the domestic cat and human RH comparative map.
Ideograms for each cat chromosome are shown to the left of each map.
Hybridization results from human on cat chromosome painting are depicted to the
left of each ideogram for comparison to the RH-derived syntenies. The extent of
RH-based physical coverage of each chromosome is not implied except where
indicated by cytogenetic localization of Type I markers on the RH map.
Orientation of RH maps relative to the chromosome is established except for the
following chromosomes: D1, E3, F1 and Y. Green arrows indicate the inferred
position of the centromere on the RH map, as determined by maximum retention
frequency-based centromeric effects and syntenic
boundaries. Loci labeled in red were ordered at odds >1000:1, those in
blue >100:1, those in black <100:1. The distances on the cat RH map
are represented by alternating black and red vertical bars, with each bar
corresponding to 50 cR5000. The length of each feline RH linkage group is listed
below each map. The human RH maps are shown on the right. RH coordinates
for the outermost markers of each human conserved homology block are listed.
Human loci positioned on the Stanford G3-based RH map are depicted by a bar
spanning the range of the same map interval in the Genebridge4-based RH.
Human ESTs which have not been associated with a named gene of known function
are listed by their UniGene cluster identifier. Feline homologues of these loci
are indicated by the prefix Fc. preceding the human cluster identifier number.
The majority of feline microsatellites are denoted by the prefix FCA or an F,
followed by a number. Dashed lines connect homologous Type I loci in both cat
and human RH maps. Gaps in the RH maps of B3 and E1 are connected by dashed
lines (no distance implied) and are bracketed by linked microsatellite loci in
the genetic linkage map.
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