Cat
Genome Project
Why The Cat
Genetic Markers
Genetic Maps
MHC
Mitochondrial Genome
Animal Model
Publications
Links
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Publications
GENETIC
MAPS:
 | Murphy,
W. J., Sun, S., Chen, Z.-Q., Yuhki, N., Hirschmann, D., Menotti-Raymond, M.,
and O'Brien, S. J.: A radiation hybrid map of the cat genome:
Implications for comparative mapping. Genome Research.
10(5):691-702, 2000. Pubmed
 | Murphy,
W. J., Sun, S., Chen, Z.-Q., Pecon Slattery, J., and O'Brien, S. J.: Extensive
conservation of sex chromosome organization between cat and human revealed
by parallel radiation hybrid mapping. Genome Res. 9(12):1223-30,
1999. Pubmed
 | Menotti-Raymond,
M., David, V. A., Lyons, L. A., Schäffer, A. A., Tomlin, J. F., Hutton, M.
K., and O'Brien, S. J.: A genetic linkage map of microsatellites in the
domestic cat (Felis catus). Genomics. 57: 9-23, 1999. Pubmed
 | Murphy,
W. J., Menotti-Raymond, M., Lyons, L. A., Thompson, M. A., and O'Brien, S.
J.: Development of a feline whole genome radiation hybrid panel and
comparative mapping of human chromosome 12 and 22 loci. Genomics. 57:
1-8, 1999. Pubmed
 | Cho,
K-W., Youn, H-Y, Okuda, M., Satoh, H., Cevario, S., O'Brien, S. J., Watari,
T., Tsujimoto, H., and Hasegawa, A.: Cloning and mapping of cat (Felis
catus) immunoglobulin and T-cell receptor genes. Immunogenetics 47:
226-233, 1998. Pubmed
 | Lyons,
L. A., Laughlin, T. F., Copeland, N. G., Jenkins, N. A., Womack, J. E., and
O'Brien, S. J.: Comparative anchored tagged sequences (CATS) for
integrative mapping of mammal genomes. Nature Genetics .15: 47-56, 1997.
Pubmed
 | O'Brien,
S. J., Wienberg, J., and Lyons, L. A.: Comparative genomics: Lessons from
cats. Trends Genet. 13: 393-399, 1997. Pubmed
 | O'Brien,
S. J.: Genetic map of Felis catus (domestic cat). In O'Brien, S.
J. (Ed.): Genetic Maps: Locus Maps of Complex Genomes, Nonhuman
Vertebrates, Sixth Edition. New York, Cold Spring Harbor
Laboratory, 1993, pp. 4.250-4.253.O'Brien, S. J.: Genetic map of the
domestic cat, Felis catus. In O'Brien, S. J. (Ed.): Genetic Maps: Locus
Maps of Complex Genomes, Nonhuman Vertebrates, Fifth Edition. New
York, Cold Spring Harbor Laboratory, 1990, pp. 4.102-4.104.
 | Gilbert,
D. A., O'Brien, J. S. and O'Brien, S. J.: Chromosomal mapping of
lysosomal enzyme structural genes in the domestic cat. Genomics 2:
329-336, 1988. Pubmed
 | O'Brien,
S. J.: Genetic map of the domestic cat, Felis catus. In
O'Brien, S. J. (Ed.): Genetic Maps, Vol. 4. New York, Cold Spring
Harbor Laboratory, 1987, pp. 482-485.
 | Berman,
E. J., Nash, W. G., Seuanez, H. N., and O'Brien, S. J.: Chromosomal
mapping of enzyme loci in the domestic cat: GSR to C2, ADA and ITPA to
A3, and LDHA-ACP2 to D1. Cytogenet. Cell Genet. 41: 114-120, 1986. Pubmed
 | O'Brien,
S. J., Haskins, M. E., Winkler, C. A., Nash, W. G., and Patterson, D. F.: Chromosomal
mapping of beta-globin and albino loci in the domestic cat: A conserved
mammalian chromosome group. J. Hered. 77: 374-378, 1986. Pubmed
 | O'Brien,
S. J. and Nash, W. G.: Genetic mapping in mammals: Chromosome map
of the domestic cat. Science 216: 257-265, 1982. Pubmed
 | O'Brien,
S. J., Nash, W. G., Simonson, J. M., and Berman, E. J.: Establishment of
a biochemical genetic map of the domestic cat (Felis catus). In
Hardy, W. D., Essex, M., and McClelland, A. J. (Eds.): Feline Leukemia
Virus. New York, Elsevier/North Holland, 1980, pp. 401-412.
 | O'Brien,
S. J. and Nash, W. G.: Somatic cell genetic analysis of enzyme
structural genes of the domestic cat (Felis catus). Carnivore
Genet. 4: 81-88, 1980. |
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Comparative
Mapping:
 | O'Brien,
S. J., et al. Comparative Genomics. Mammalian Radiation. Genome Maps X.
Science, 286, Suppl., 1999.O'Brien, S. J., Menotti-Raymond, M., Murphy, W.
J., Nash, W. G., Wienberg, J., Stanyon, R., Copeland, N. G., Jenkins, N. A.,
Womack, J. E., and Graves, J. A. M., "The Promise of Comparative
Genomics in Mammals", Science 286:458-481, 1999.
 | O'Brien,
S. J., Cevario, S. J., Martenson, J. S., Thompson, M. E., Nash, W. G.,
Chang, E., Graves, J. A. M., Spencer, J. A., Cho, K.-W., Tsujimoto, H., and
Lyons, L. A.: Comparative gene mapping in the domestic cat (Felis catus).
J. Hered. 88: 408-414, 1997. Pubmed
 | Dean,
M., Kozak, C., Robbins, J., Callahan, R., O'Brien, S., and Vande Woude, G.
F.: Chromosomal localization of the met proto-oncogene in the mouse
and cat genome. Genomics 1: 167-173, 1987. Pubmed
 | Brownell,
E., Kozak, C. A., Fowle, J. R., III, Modi, W. S., Rice, N. R., and O'Brien,
S. J.: Comparative genetic mapping of cellular rel sequences in man,
mouse, and the domestic cat. Am. J. Hum. Genet. 39: 194-202, 1986. Pubmed
 | O'Brien,
S. J.: Molecular genetics in the domestic cat and its relatives.
Trends Genet. 2: 137-142, 1986.
 | Papas,
T. S., Watson, D. K., Sacchi, N., O'Brien, S. J., and Ascione, R.: The
mammalian ets genes: Two unique chromosomal locations in cat, mice and man
and novel translocated position in human leukemias. In Hagenbeck, A. and
Lowenberg, B. (Eds.): Minimal Residual Disease in Acute Leukemia:
1986. Boston, Martinus Nijhoff/Dodrecht, pp. 23-42.
 | Watson,
D. K., Smith, M. J., Kozak, C., Reeves, R., Gearhart, J., Nunn, M. F.,
Nash, W., Fowle, J. R., III, Duesberg, P., Papas, T. S., and O'Brien, S. J.:
Conserved chromosomal positions of dual domains of the ets proto-oncogene in
cats, mice and man. Proc. Natl. Acad. Sci. USA 83: 1792-1796,
1986. Pubmed
 | O'Brien,
S. J., Reeves, R. H., Simonson, J. M., Eichelberger, M. A., and Nash, W. G.:
Parallels of genomic organization and endogenous retrovirus organization in
cat and man. Develop. Genet. 4: 341-354, 1984.
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General:
 | O'Brien,
S. J., Gail, M. H., and Levin, D. L.: Correlative genetic variation in
natural populations of cats, mice and men. Nature 288: 580-583, 1980.
Pubmed
 | O'Brien,
S. J.: The extent and character of biochemical genetic variation in
the domestic cat (Felis catus). J. Hered. 71: 2-8, 1980. |
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Molecular
Evolution:
 | O'Brien,
S.J.: The family line: The human-cat connection. National Geographic
Magazine 191: 77-85, 1997.
 | O'Brien,
S. J.: Molecular evolution of cats. In Seidensticker, J. (Ed.):
Great Cats: Majestic Creatures of the Wild. Sydney, Australia, Weldon
Owen Pty Ltd., 1991, p. 146.
 | O'Brien,
S. J., Nash, W. G., Winkler, C. A., and Reeves, R. H.: Genetic analysis in
the domestic cat as an animal model for inborn errors, cancer and evolution.
In Migaki, G., Desnick, R. J., and Patterson, D. F. (Eds.): Animal
Models of Inherited Metabolic Diseases. New York, Alan R. Liss, 1982,
pp. 67-90. Pubmed |
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Cat
Major Histocompatibility Complex:
 | Yuhki,
N., Winkler, C., and O'Brien, S. J.: MHC genes of the domestic cat.
In Srivastava, R., Ram, B. P., and Tyle, P. (Eds.): Immunogenetics of the
Major Histocompatibility Complex. New York, VCH Publishers, 1991, pp.
348-367.
 | Yuhki,
N., Heidecker, G. F., and O'Brien, S. J.: Characterization of MHC cDNA
clones in the domestic cat: Diversity and evolution of class I genes.
J. Immunol. 142: 3676-3682, 1989. Pubmed
 | Winkler,
C., Schultz, A., Cevario, S., and O'Brien, S. J.: Genetic characterization
of FLA, the cat major histocompatibility complex. Proc. Natl. Acad. Sci. USA
86: 943-947, 1989. Pubmed
 | Yuhki,
N. and O'Brien, S. J.: Molecular characterization and genetic mapping
of class I and class II MHC genes of the domestic cat. Immunogenetics 27:
414-425, 1988. Pubmed |
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Cat
Mitochondrial DNA:
 | Lopez,
J. V., Yuhki, N., Masuda, R., Modi, W. S., and O'Brien, S. J.: Numt, a
recent transfer and tandem amplification of mitochondrial DNA to the nuclear
genome of the domestic cat. J. Mol. Evol. 39:174-190, 1994. Pubmed
 | Lopez,
J. V., Cevario, S., and O'Brien, S. J.: Complete nucleotide sequence of the
domestic cat (Felis catus) mitochondrial genome and a transposed mtDNA
tandem repeat (Numt) in the nuclear genome. Genomics 33: 229-246, 1996
Pubmed |
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Forensics:
 | Menotti-Raymond,
M., David, V. A., Stephens, J. C., and O'Brien, S. J.: Genetic
individualization of domestic cats using feline STR loci for forensic
analysis. J. Forensics Sci. 42: 1039-1051, 1997.
 | Menotti-Raymond,
M.A., David, V.A., and O'Brien, S.J.: Pet cat hair implicates murder
suspect. Nature 386: 774, 1997. Pubmed |
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Viruses:
 | Carpenter,
M. A., Brown, E. W., MacDonald, D. W., and O'Brien, S. J.: Phylogeographic
patterns of feline immunodeficiency virus genetic diversity in the domestic
cat. Virol. 251: 234-243, 1998. Pubmed
 | VandeWoude,
S., O'Brien, S.J., Langelier, K., Hardy, W.D., Slattery, J.P., Zuckerman, E.
E., and Hoover, E.A.: Growth of lion and puma lentiviruses in domestic cat
cells and comparisons with FIV. Virology 233: 185-192, 1997. Pubmed
 | VandeWoude,
S., O'Brien, S.J., and Hoover, E.A.: Infectivity of lion and puma
lentiviruses for domestic cats. J Gen. Virol. 78: 795-800, 1997. Pubmed
 | Reeves,
R. H., Nash, W. G., and O'Brien, S. J.: Genetic mapping of endogenous
RD-114 retroviral sequences of the domestic cat. J. Virol. 56:
303-306, 1985. Pubmed
 | O'Brien,
S. J. and Simonson, J. M.: Bvr-1: A restriction locus of a type
C RNA virus in the feline cellular genome: Pleiotropic restriction of
endogenous BALB virus in cat x mouse somatic cell hybrids. J. Exp.
Med. 147: 219-232, 1978. Pubmed
 | O'Brien,
S. J. and Boone, C. W.: Expression of feline leukemia virus antigens on cat
lymphoma cells: Kinetics of biosynthesis. J. Gen. Virol. 35: 511-523,
1977. Pubmed
 | O'Brien,
S. J.: Bvr-1, a restriction locus of a type C RNA virus in the feline
cellular genome: Identification, location, and phenotypic characterization
in cat x mouse somatic cell hybrids. Proc. Natl. Acad. Sci. USA 73:
4618-4622, 1976. Pubmed |
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Reproduction:
 | Donoghue,
A. M., Johnston, L. A., Goodrowe, K. L., O'Brien, S. J. and Wildt, D. E.:
Influence of day of estrous on egg viability and comparative efficiency of
in vitro fertilization in domestic cats in natural or gonadotrophin-induced
oestrus. J. Reprod. Fertil. 98: 85-90, 1993. Pubmed
 | Johnston,
L. A., Donoghue, A. M., O'Brien, S. J., and Wildt, D. E.: Influence of
culture medium on in vitro maturation and fertilization in the domestic cat.
Theriogenology 80: 829-839, 1993.
 | Johnston,
L. A., Donoghue A. M., O'Brien, S. J., and Wildt, D. E.: Influence of
temperature and gas atmosphere on in vitro fertilization and embryo
development in domestic cats. J. Reprod. Fertil. 92: 377-382, 1991. Pubmed
 | Johnston,
L. A., Donoghue A. M., O'Brien, S. J., and Wildt, D. E.: Culture medium and
protein supplementation influence in vitro fertilization and embryo
development in the domestic cat. J. Exp. Zool. 257: 350-359,
1991. Pubmed
 | Johnston,
L. A., O'Brien, S. J., and Wildt, D. E.: In vitro maturation and
fertilization of domestic cat follicular oocytes. Gamete Res. 24:
343-356, 1989. Pubmed
 | Goodrowe,
K. L., Wall, R. J., O'Brien, S. J., Schmidt, P. M., and Wildt, D. E.:
Developmental competence of domestic cat follicular oocytes after
fertilization in vitro. Biol. Reprod. 39: 355-372, 1988. Pubmed |
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