| Virus Archive |
| Gene* | Origin | Expression | Function | Reference | Contact** |
| AKT1-HA, myristylated & activated | mouse | IHC | Orsulic | ||
| cyclin D1 | human | Western | Li | ||
| c-myc-HA | human | Western | transforming | Li | |
| c-Myc | human | Western | Orsulic | Orsulic | |
| K-RasG12D, HA tagged | human | Western | yes | Lewis | |
| K-RasG12D | human | Western | Orsulic | Orsulic | |
| FGF3 | mouse | Li | |||
| Wnt-1, HA tagged | mouse | IHC, IF | transforming | Dunn | Li, Pavan |
| b-catenin S37A-HA | human | Western | Li, Pavan, Williams | ||
| b-catenin S37-V5 |
human |
|
|
Chamorro |
|
| b-catenin WT, -V5 |
human |
Chamorro | |||
| Middle TAG | polyoma | Yes | Holland | Li, Holland | |
| p53R273L | mouse | Western | Yes | Li | |
| dnE-cadherin, myc tagged | mouse | Li | |||
| Luciferase |
Yes |
Li | |||
| LacZ | Yes | Yes | Dunn | Li, Pavan | |
| TAG |
SV40 |
Yes | Li | ||
| E1A | Li | ||||
| TCF4-V5 | Chamorro | ||||
| LEF1 |
Holland |
||||
| CDK4 | human | IHC | Holland | ||
| Mdm2 | mouse | Holland | |||
| VEGF | Holland | ||||
| EGFR* | human | Western, IHC | Yes | Holland | Holland |
| bFGF | mouse | IHC | Yes | Holland | Holland |
| Cre | Yes | Holland | |||
| AP | human | Yes | Yes | Federspiel | Holland, Orsulic, Hughes |
| Puromycin | Yes | Holland | |||
| tyrosinase | Western | Hughes | |||
| Bcl-6, flag tagged | human | Western (97kD) | Art Schaffer/Staudt lab | ||
| Bcl-6 zinc finger domain, flag tagged | human | Western (<30kD) | Art Schaffer/Staudt lab | ||
| GFP |
C. Cepko |
||||
| CDK6 | human | Marty Grossel | |||
| cdk6R31C | human | Marty Grossel | |||
| PKC-alpha | Western | Bob Glazer | |||
* Most of the viruses are made using RCASBP(A) as the expression vector.
The complete and verified sequence of this vector is soon going to be made
available by Steve
Hughes. Some of them were generated in derivatives of RCASBP(A).
Two of them are RCAS-Y an RCAS-X. They are the results of insertion
of unique cloning sites (NotI-PmeI-PacI-ClaI for RCAS-Y and ClaI-PacI-PmeI-NotI
for RCAS-X) in the ClaI cloning site of RCASBP(A).
Many viruses are not published; therefore, some of them may not be available.
**Mario Chamorro: chamorrom@mskcc.org
Eric Holland: hollande@mskcc.org
Brian Lewis: lewisb@mskcc.org
Yi Li: liyi@breastcenter.tmc.edu
Sandra Orsulic: SORSULIC@PARTNERS.ORG
Bill Paven: bpavan@nhgri.nih.gov
Blue-coded viruses have maps online. Click on the gene name to see the maps.
| TVA Technology | Virus Archive | TVA Transgenic Lines | TVA Workshops & Attendees |