| National Cancer Institute | Laboratory of Receptor Biology and Gene Expression | National Institutes of Health |
Dr. Hager received his Ph.D. in Genetics at the University of Washington, where he studied phage genetics under the direction of Dr. Ben Hall. He pursued postdoctoral studies in gene regulation with Dick Epstein at the Institut de Biologie Moleculaire in Geneva, and with Dr. William Rutter at UCSF. He began his career at the NIH in the Laboratory of Tumor Virus Genetics, NCI, where he carried out the first molecular cloning of retroviruses. He also reported the first identification of steroid responsive regulatory elements, and first drew attention to the role of chromatin remodeling in gene activation by steroid receptors. Dr. Hager is currently Chief of the Laboratory of Receptor Biology and Gene Expression in the Division of Basic Sciences, NCI. His primary interests include the role of chromatin structure in gene regulation, mechanisms of steroid receptor function, the deregulation of oncogenes during carcinogenesis,and the architecture of active genes in the interphase nucleus.
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