Division of Basic Sciences,
National Cancer Institute,
National Institutes of Health

Experimental SFM Image of a Glutaraldehyde-fixed Chromatin Fiber.

A glutaraldehyde-fixed chromatin fiber deposited on mica in 5 mM TEA-HCl, pH 7.0. The measured height of the nucleosomes is around 3 nm, which determines the degree of flattening for the model fiber in B.

Yang, G., Leuba, S. H., Bustamante, C., Zlatanova, J. and van Holde, K. Role of linker histones in extended chromatin fibre structure. Nat Struct Biol. 1(11) 761-763 1994

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