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Last Update: 2007.10.03

1. Pastan, I., Lee, B., Jung, S.-H., and Brinkmann, U.: Recombinant disulfide-stabilized polypeptide fragments having binding specificity. United States Patent number 5,747,654, awarded May 5, 1998.

2. Pastan, I., Benhar, I., Padlan, E. A., Jung, S.-H., and Lee, B.: Humanized B3 antibody fragments, fusion proteins, and uses thereof. United States Patent number 5,889,157, awarded March 30, 1999.

3. Pastan, I., Lee, B., Jung, S.-H., and Brinkmann, U.: Recombinant disulfide-stabilized polypeptide fragments having binding specificity. United States Patent number 6,147,203, awarded November 14, 2000.

4. Pastan, I., Fitzgerald, D., and Lee, B.: Methods of inhibiting the growth of cells bearing Lewis antigens using B1, B3, or B5 targeted immunoconjugates. United States Patent number 6,287,562, awarded September 11, 2001.

5. Pastan, I., Lee, B., Jung, S.-H., and Brinkmann, U.: Methods of making recombinant disulfide-stabilized polypeptide fragments having binding specificity. United States Patent number 6,558,672, awarded May 6, 2003.

6. Pastan, I., Essand, M., Lee, B., Vasmatzis, G., Wolfgang, C., Brinkmann, U: T-cell receptor gamma. alternate reading frame protein, (TARP) and uses thereof. United States Patent number 7,052,703, awarded May 30, 2006.

Patents Pending:

1. Pastan, I., Brinkmann, U., Vasmatzis, G., Lee, B.: PAGE-4, an X-linked GAGE-like gene expressed in normal and neoplastic prostate, testis, and uterus, and uses therefore. United States Patent pending. 09/763,393, 7/30/2001.

2. Patan, I., Tsutsumi, Y., Onda, M., Nagata, S., Lee, B., Kreitman, R.: PEGylation of linkers improves antitumor activity and reduces toxicity of immunoconjugates. United States and EU Patent pending. 01948294.2, 8/6/2001.

3. Pastan, I., Liu, X,-F., Bera, T. K., Lee, B., Egland, K. A.: XAGE-1, a gene expressed in multiple cancers, and uses thereof. United States Patent pending. 60/229,684, 8/31/2001.

4. Pastan, I., Olsson, P., Bera, T. K., Essand, M., Lee, B.: GHEP, a gene highly expressed in normal and neoplastic prostate, and uses thereof. United States Patent pending. 60/239,413, 10/10/2001.

5. Tapan K. Bera, Hiroshi Maeda, Curt D. Wolfgang, Dennis Gately, Kandasamy Hariharan, Vasantha Kumar, Byungkook Lee and Ira Pastan: NGEP, a novel gene specifically expressed in prostate cancer and normal prostate. United States Patent pending. 60/336,308,

6. Ira Pastan, Kristi Egland, James Vincent, Byungkook Lee and Robert Strausberg: BASE: a new cancer gene, and methods and uses thereof. United States Patent pending. 60/432,531, 12/10/2002.

7. Ira Pastan, Kristi Egland, , Byungkook Lee and James Vincent: Gene expressed in breast cancer and methods of use. United States and International Patents pending. 60/493,522, 7/31/2003.

8. Ira H. Pastan, Tapan K. Bera and Byungkook Lee: MRP9 and its use in detecting and treating cancer. United States Patent pending. 60/350,053 and 60/375,121, 1/15/2003.

9. Ira H. Pastan, Tapan K. Bera, Curt D. Wolfgang, Byungkook Lee, and James Vincent: Gene expressed in prostate cancer and methods of use. United States and European Patents pending. 10/495,663, 5/12/2004.

10. Ira H. Pastan, Tapan K. Bera, and Byungkook Lee: Antibodies that bind POTE and uses thereof. United States and European Patents pending. 60/546,058, 2/17/2005.

11. Ira H. Pastan, Masanori Onda, Satoshi Nagata, David Fitzgerald, Robert Kreitman and Byungkook Lee: Mutated Pseudomonas exotoxins with reduced antigenicity. United States Provisional Patent Application. 60/703,798, 7/29/2005.

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