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Last Update: 2006.09.08 | Recent Publication (sorted by research topics) Present ~ 2004 | 2003~ 2000 | 1999 ~ 1996 | 1995 ~ 1993 1995 Reiter, Y., Brinkmann, U., Jung, S.-H., Pastan, I., and Lee, B.: Disulfide-stabilization of antibody Fv: Computer predictions and experimental evaluation. Protein Eng. 8 : 437-42, 1995. [PubMed Abstract] Lee, B.: New approaches for analyzing solvent reorganization and hydrophobicity.Methods in Enzymology , Vol. 259, Chapter 25, pp. 555-576, 1995. Kurochkina, N., and Lee, B.: Hydrophobic potential by pair-wise surface area sum. Protein Eng. 8 : 437-442, 1995. [PubMed Abstract] Reiter, Y., Kurucz, I., Brinkmann, U., Jung, S.-H., Lee, B., Segal, D.M., and Pastan, I.: Construction of a functional disulfide stabilized TCR Fv indicates that antibody and TCR Fv frameworks are very similar in structure. Immunity 2 :281-287,1995. [PubMed Abstract] 1994 Benhar, I., Padlan, E.A., Jung, S.-H., Lee, B., and Pastan, I.: Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38. Proc. Natl. Acad. Sci. USA 91 : 12051-12055, 1994. [PubMed Abstract] Kurochkina, N.A., Kang, H.S., and Lee, B.: Experiences with dihedral angle space Monte Carlo search for small protein structures. Statistical Mechanics, Protein Structure, and Protein Substrate Interactions , Doniach, S. ed., Plenum, New York, NY, pp. 147-157, 1994 Roscoe, D.M., Jung, S.-H., Benhar, I., Pai, L. Lee, B., and Pastan, I.: Primate antibody response to immunotoxin: serological and computer-aided analysis of epitopes on a truncated form of Pseudomonas exotoxin. Infect. Immun. 62 : 5055-5065, 1994. [PubMed Abstract] Sergeev, Y. and Lee, B.: Alignment of beta-barrels in (a/b)8 proteins using hydrogen-bonding pattern. J. Mol. Biol. 244 : 168-182, 1994. [PubMed Abstract] Kreitman, R.J., Puri, R.K., Leland, P., Lee, B., and Pastan, I.: Site-specific conjugation to interleukin 4 containing mutated cysteine residues produces interleukin 4-toxin conjugates with improved binding and activity. Biochemistry 33 : 11637-11644, 1994. [PubMed Abstract] Madan, B., and Lee, B.: Role of hydrogen bonds in hydrophobicity: the free energy of cavity formation in water models with and without the hydrogen bonds. Biophysical Chem. 51 : 279- 289, 1994. [Abstract] Lee, B.: Enthalpy-entropy compensation in the thermodynamics of hydrophobicity. Biophysical Chem. 51 : 271-278, 1994. [Abstract] Lee, B.: Relation between volume correction and the standard state. Biophysical Chem. 51 : 263-269, 1994. [Abstract] Reiter, Y., Brinkmann, U., Jung, S.-H., Lee, B., Kasprzyk, P.G., King, C.R., and Pastan, I.: Improved binding and anti-tumor activity of a recombinant anti-erbB2 immunotoxin by disulfide-stabilization of the Fv fragment. J. Biol. Chem. 269 : 18327-18331, 1994. [PubMed Abstract] Reiter, Y., Brinkmann, U., Kreitman, R.J., Jung, S.-H., Lee, B., and Pastan, I.: Stabilization of the Fv fragments in recombinant immunotoxins by disulfide bonds engineered into conserved framework regions. Biochemistry 33 : 5451-5459, 1994. [PubMed Abstract] Reiter, Y., Brinkmann, U., Webber, K.O., Jung, S.-H., Lee, B., and Pastan, I.: Engineering disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv. Protein Engineering 7 : 697-704, 1994. [PubMed Abstract] Jung, S.-H., Pastan, I., and Lee, B.: Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3. Proteins: Structure, Genetics and Function 19 : 35-47, 1994. [PubMed Abstract] 1993 Brinkmann, U., Reiter, Y., Lee, B., Jung, S.-H., and Pastan, I.: A recombinant immunotoxin containing a disulfide-stabilized Fv fragment (dsFv) nd a truncated form of Pseudomonas exotoxin. Proc. Natl. Acad. Sci. USA. 90 : 7538-7542, 1993. [PubMed Abstract] McPhie, P., Parkison, C. Lee, B., and Cheng, S.-Y.: Structure of the hormone binding domain of human b1 thyroid hormone nuclear receptor: Is it an a/b barrel? Biochemistry 32 : 7460-7465, 1993. [PubMed Abstract] Suh, E., Lee, B., Narahari, B., Choudhary, A.N., and Martino, R.: Parallel computation of solvent accessible surface area of protein molecules. Proceeding of the Seventh International Parallel Processing Symposium , pp. 685-689, 1993. Brinkmann, U., Lee, B., and Pastan, I.: Cytotoxicity of recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin. J. Immunol. 150 : 2774-2782, 1993. [PubMed Abstract] Lee, B.: Estimation of the maximum change in stability of globular proteins upon mutation of a hydrophobic residue to another of smaller size. Protein Science ,2: 733-738, 1993. [PubMed Abstract] Juretic, D., Lee, B., Trinajstic, N., and Williams, R.W.: Conformational preference functions for predicting helices in membrane proteins. Biopolymers ,33 : 255-273, 1993. [PubMed Abstract] Kang, H.S., Kurochkina, N.A., and Lee, B.: Estimation and use of protein backbone angle probabilities. J. Mol. Biol. 229 : 448-460, 1993. [PubMed Abstract] | |||
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