Table 1. Clusters with 3 or more inserts and cluster specificity index of less than 4.

 

Selected Cluster name

No. of Inserts

No. of zeroes*

Organ or tumor other than prostate 

Putative IDs or EST Names from the Cluster

 

210

115

lung , breast

pancreas

Prostate Specific Antigen (PSA)

Glandular Kallikrein

 

207

5

lung

Prostate Secreted Seminal Plasma Protein

 

109

35

fetal heart, lung

Prostatic Acid Phosphatase

 

13

0

brain, placenta

T-Cell Receptor Gamma Chain C Region

 

12

12

kidney

Semenogelin 1 and Semenogelin II

 

12

0

senescent fibroblast, testis, lung

ng75f05 nc35a03 nj93c05 nj65e04 ng89g12 nh69c06 nj09a12 nj15a05 nc35h08 ng95e05 ng77b09

C1

6

12

 

nc16a06 nc19c11 nc46c10 nc45d06 nc13d11 nc47f03

 

6

8

colon

Adenylate Kinase Isoenzyme 1

 

6

0

fetal heart, melanocyte

SNAP-23 I and II

C2

5

8

 

nc14b02 nc04c08 nc71b05 nc06e12 nc71b06

C3

5

7

 

nc39f01 nc39e12 nc39f02 nc39f08 nc39f10

nan

5

7

 

nc45b05 nc47g07 nc50e01 nc50e02 nc46b12

nan

5

5

 

ni72d09 ni72e05 ni67h04 ni62e03 ni75f09

 

5

1

muscle, fetal liver-spleen

EST82997 EST82999 nc14b12 nc35g10 nc13f10

 

5

0

colon , colon mucosa, pancreatic islet

nc08h07 nj62g06 nj52h03 nj97a07 nc35e08

repr

4

6

 

nc21c02 nc21g08 nc25h05 nc27d09

C4

4

6

 

nc09h02 nc11c01 nc27e02 nc11g03

C7

4

5

 

ng90g10 nc44h02 nc51d11 nc45e06

nan

4

4

 

nh45f08 nh46h11 nh52b05 nh50b02

 

4

0

Jurkat T-cell, brain, fetal liver-spleen

Ganglioside GM2 Activator Precursor

 

4

0

brain, alveola

Neuropeptide Y Precursor

 

4

0

placenta, mixed, fetal liver-spleen

nc27g01 nc79f08 nc33g02 nh32c06

 

4

0

breast, fetal liver-spleen

nc76b03 nc76b02 nc78c03 nc78a03

 

4

0

Ewing's-sarc, mixed, colon

Homeobox Protein Hox-D13

C5

3

6

 

nc19e02 nc26f02 nc09b07

C6x

3

6

nc49e12 nc50a11 nc50a10

nan

3

6

 

nc45b06 nc47e09 nc47c02

 

3

5

 

ErbB-3 Receptor Protein-Tyrosine Kinase

C8

3

5

 

nc47a06 nc51c05 nc47d03

repr

3

5

 

nc09b11 nc26c10 nc17g01

repr

3

5

 

nc35f10 nc78a06 nj45e02

 

3

5

 

nc74f10 nc75f10 nj94a02

 

3

5

 

SYT (translocated gene in synovial sarcoma)

 

3

5

 

Androgen Receptor

repr

3

4

 

nc23d04 nc19h07 nc09a11

repr

3

4

 

nc60c07 nc60h01 nc60g08

 

3

4

 

nc71d01 nc70h01 nc71d02

 

3

4

 

nc74f01 nc72h04 nc72h02

 

3

4

 

ng86d03 nc45e08 nc46g10

 

3

3

fetal lung

nc21f01 nc23e02 nc26f12

 

3

3

 

nc39h05 nc35d09 nc32a05

repr

3

3

 

ng93g03 ng94c03 nj53c11

repr

3

3

 

nh55d12 ni75g08 nh67b02

 

3

3

 

nh61a10 nh71c03 nh72d04

 

3

3

 

nh38g12 nh45b08 nh48a05

 

3

3

 

nh45c07 nh46d03 nh50e10

 

3

3

 

nh46c02 nh46c03 nh48c10

 

3

3

 

nc51d10 nc51h05 nc51h01

repr

3

3

 

nh35e03 nh30d08 nh31c03

 

3

2

infant brain, melanocytes, placenta

nc60h10 nc63c08 nc60h12

 

3

2

neuroepithelium

Retrovirus Related Pol Polyprotein

 

3

2

mixed

Nir Like Gene Involved In Dentrification

 

3

2

aorta

nc76e10 nc45f05 nj80d07

 

3

1

infant brain, pregnant uterus

nc73e05 nc47h12 nc47b12

 

3

1

lung

Hypothetical 59.2 kD Protein IN

 

3

1

Ewing's sarcoma

Alcohol Dehydrogenase Class II PI Chain

 

* Zeroes are the ESTs with zero non-prostate hits.   Tumor libraries are in italics. x The C6 cluster was not analyzed because the selected clone (nc50a10) contained the wrong insert. The actual insert was found to belong to the psspp cluster. n EST clones from these clusters were not available. r These clusters contain ESTs with a warning for the presence of some kind of repetitive element.

 

 

 



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Abstract

Bibliography

Molecular Modeling Section
Laboratory of Molecular Biology
National Cancer Institute
National Institutes of Health